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has-very-light-gray-background-color\">\u30b7\u30ca\u30d7\u30b9\u5f8c\u306e\u30bb\u30ed\u30c8\u30cb\u30f31A\u53d7\u5bb9\u4f53\u306e\u6d3b\u6027\u5316\u306f\u3001\u904e\u5206\u6975\uff08\u6291\u5236\uff09\u52b9\u679c\u3092\u3082\u305f\u3089\u3057\u307e\u3059\uff08Andrad\uff09\u3002\u30b7\u30ca\u30d7\u30b9\u5f8c\u306e2A\u53d7\u5bb9\u4f53\u306e\u6d3b\u6027\u5316\u304c\u8131\u5206\u6975\uff08\u8208\u596e\uff09\u52b9\u679c\u3092\u3082\u305f\u3089\u3059\u306e\u3068\u5bfe\u7167\u7684\u3067\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u307e\u305f\u3001\u901a\u5e38\u306e\u72b6\u614b\u306e\u8133\u3067\u306f\u3001<strong><span style=\"font-family: 'arial black', sans-serif;\">\u5927\u8133\u76ae\u8cea\u304a\u3088\u3073\u8fba\u7e01\u7cfb\u9818\u57df\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u6a5f\u80fd\u3092\u652f\u914d\u3057\u3066\u3044\u308b\u306e\u306f1A\u53d7\u5bb9\u4f53\u3067\u3042\u308b<\/span><\/strong>\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059(Puig)\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u6975\u7aef\u306a\u30b9\u30c8\u30ec\u30b9\u4e0b\u3067\u306f\u30011A\u53d7\u5bb9\u4f53\u306f\u30c0\u30a6\u30f3\u30ec\u30ae\u30e5\u30ec\u30fc\u30c8\u3055\u308c\uff08Berton\uff09\u30012A\u53d7\u5bb9\u4f53\u306f\u30a2\u30c3\u30d7\u30ec\u30ae\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3055\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08Benekareddy\uff09\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u8133\u5185\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u4f1d\u9054\u304c\u6e1b\u5c11\u3059\u308b\u3068\u3001\u885d\u52d5\u7684\u3067\u653b\u6483\u7684\u306a\u884c\u52d5\u304c\u5897\u52a0\u3057\u307e\u3059\uff08Audero\uff09\u3002\u30bb\u30ed\u30c8\u30cb\u30f3\u306b\u3088\u308b\u653b\u6483\u6027\u3068\u885d\u52d5\u6027\u306e\u7de9\u548c\u52b9\u679c\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u5f8c1A\u53d7\u5bb9\u4f53\u306e\u30b7\u30b0\u30ca\u30eb\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08Sanchez and Hyttel\uff09\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u30b7\u30ca\u30d7\u30b9\u5f8c1A\u53d7\u5bb9\u4f53\u306f\u3001\u8fba\u7e01\u7cfb\u9818\u57df\u3001\u7279\u306b\u6d77\u99ac\u306b\u9ad8\u5bc6\u5ea6\u306b\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\uff08Pazos and Palacios\uff09\u30021A\u53d7\u5bb9\u4f53\u3092\u523a\u6fc0\u3059\u308b\u3053\u3068\u3067\u3001\u9310\u4f53\u7d30\u80de\u306e\u6d3b\u52d5\u306f\u6291\u5236\u3055\u308c\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u30b7\u30ca\u30d7\u30b9\u5f8c1A\u53d7\u5bb9\u4f53\u306e\u6291\u5236\u4f5c\u7528\u304c\u3001\u5927\u8133\u8fba\u7e01\u7cfb\u306e\u904e\u6d3b\u52d5\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u4e0d\u5b89\u304c\u8efd\u6e1b\u3055\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08Dong\u3089\u30011998\uff09\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u3084SSRI\u306e\u6301\u7d9a\u6295\u4e0e\u306f\u3001\u8fba\u7e01\u7cfb\u306e\u53cd\u5fdc\u6027\u306e\u4f4e\u4e0b\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u3067\u3001\u4e0d\u5b89\u3092\u8efd\u6e1b\u3057\u307e\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u885d\u52d5\u6027\u306e\u7de9\u548c\u306b\u95a2\u9023\u3057\u3066\u3001\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u306e\u6295\u4e0e\u304c\u6442\u98df\u969c\u5bb3\u306b\u6709\u52b9\u3067\u3042\u3063\u305f\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u307e\u3059\uff08Okita\uff09\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u30d1\u30cb\u30c3\u30af\u969c\u5bb3\u60a3\u8005\u306f\u30bb\u30ed\u30c8\u30cb\u30f31A\u53d7\u5bb9\u4f53\u306e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059[Lesch]\u3002 \u3055\u3089\u306b\u3001\u672a\u6cbb\u7642\u306e\u30d1\u30cb\u30c3\u30af\u969c\u5bb3\u60a3\u8005\u306b\u304a\u3044\u30665-HT1A\u7d50\u5408\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059[Nash,Neumeister]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u306f\u3001PTSD\u306e\u52d5\u7269\u30e2\u30c7\u30eb\u3067\u6050\u6016\u306e\u6d88\u53bb\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u3067\u4e0d\u5b89\u3092\u8efd\u6e1b\u3059\u308b\u3068\u3044\u3046\u6cbb\u7642\u52b9\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u305f\u3060\u3057\u3001\u4e0d\u5b89\u306e\u6cbb\u7642\u306b\u304a\u3051\u308b\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u306e\u4e3b\u306a\u6b20\u70b9\u306f\u3001\u77ed\u3044\u534a\u6e1b\u671f\u30681\u9031\u9593\u307e\u305f\u306f2\u9031\u9593\u306e\u9045\u767a\u6027\u3067\u3059[Godbout]\u3002\u3053\u308c\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u524d1A\u53d7\u5bb9\u4f53\u306e\u8131\u611f\u4f5c\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u6700\u8fd1\u884c\u308f\u308c\u305f\u7121\u4f5c\u70ba\u5316\u975e\u76f2\u691c\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u82e5\u5e74\u8005\u306e\u793e\u4f1a\u4e0d\u5b89\u969c\u5bb3\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u304c\u30bb\u30eb\u30c8\u30e9\u30ea\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u975e\u52a3\u6027\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059[Huang]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u4ee5\u4e0a\u3001\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u306f\u3001PTSD\u3084SAD\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u6709\u52b9\u306a\u6cbb\u7642\u85ac\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u3046\u3064\u75c5\u3067\u306f\u3001MAOI\u3084\u4e09\u74b0\u7cfb\u6297\u3046\u3064\u85ac\u3001SSRI\u3001\u30ea\u30c1\u30a6\u30e0\u3001\u30d0\u30eb\u30d7\u30ed\u9178\u306a\u3069\u306f\u3001\u76f4\u63a5\u30fb\u9593\u63a5\u306b\u30b7\u30ca\u30d7\u30b9\u5f8c1A\u53d7\u5bb9\u4f53\u30b7\u30b0\u30ca\u30eb\u3092\u5897\u52a0\u3055\u305b\u307e\u3059[Savitz]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u307e\u305f\u6b7b\u5f8c\u7814\u7a76\u3067\u3001\u81ea\u6bba\u60a3\u8005\u3067\u306f1A\u53d7\u5bb9\u4f53\u306e\u6570\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u3066\u304a\u308a\u3001PET\u30b9\u30ad\u30e3\u30f3\u5206\u6790\u306b\u3088\u308a1A\u53d7\u5bb9\u4f53\u306e\u7d50\u5408\u89aa\u548c\u6027\u306e\u4f4e\u4e0b\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059[Savitz]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u3055\u3089\u306b\u30011A\u53d7\u5bb9\u4f53\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u7814\u7a76\u306b\u3088\u308a\u30011A\u53d7\u5bb9\u4f53\u306e\u6a5f\u80fd\u969c\u5bb3\u304c\u3046\u3064\u75c5\u306e\u6839\u672c\u7684\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3042\u308b\u3068\u3044\u3046\u4eee\u8aac\u304c\u7acb\u3066\u3089\u308c\u3066\u3044\u307e\u3059[Savitz]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u3046\u3064\u75c5\u306e\u7de9\u548c\u306b\u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53\u306e\u4e2d\u3067\u3082\u7279\u306b1A\u81ea\u5df1\u53d7\u5bb9\u4f53\u306e\u8131\u611f\u4f5c\u304c\u91cd\u8981\u3067\u3001\u3053\u308c\u3092\u4ecb\u3057\u3066\u30bb\u30ed\u30c8\u30cb\u30f3\u304c\u5f79\u5272\u3092\u679c\u305f\u3059\u3068\u3044\u3046\u8aac\u304c\u5531\u3048\u3089\u308c\u3066\u3044\u307e\u3059[Schatzberg,Drago]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u6297\u7cbe\u795e\u75c5\u85ac\u306b\u3088\u308b\u5927\u8133\u76ae\u8cea\u3067\u306e\u30c9\u30d1\u30df\u30f3\u653e\u51fa\u306b\u306f\u30011A\u53d7\u5bb9\u4f53\u306e\u6d3b\u6027\u5316\u304c\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u304c\u3001\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f[Newman-Tancredi]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">1A\u53d7\u5bb9\u4f53\u306e\u30d1\u30fc\u30b7\u30e3\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u3067\u3042\u308b\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u306f\u3001\u30cf\u30ed\u30da\u30ea\u30c9\u30fc\u30eb\u3067\u6cbb\u7642\u3092\u53d7\u3051\u305f\u7d71\u5408\u5931\u8abf\u75c7\u60a3\u8005\u306e\u9670\u6027\u75c7\u72b6\u3092\u8efd\u6e1b\u3057\u307e\u3059 \u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u305d\u306e\u52b9\u679c\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u795e\u7d4c\u30eb\u30fc\u30d7\u3092\u4ecb\u3057\u3066\u9593\u63a5\u7684\u306b\u76ae\u8cea\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u795e\u7d4c\u4f1d\u9054\u3092\u5897\u5f37\u3059\u308b\u3053\u3068\u306b\u3088\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059[Saito\u3001Li]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u6297\u7cbe\u795e\u75c5\u85ac\u306e\u3046\u3061\u3001\u30af\u30ed\u30b6\u30d4\u30f3\u3001\u30af\u30a8\u30c1\u30a2\u30d4\u30f3\u3001\uff08\u30b8\u30d7\u30e9\u30b7\u30c9\u30f3&#8211;\u672c\u90a6\u672a\u767a\u58f2\uff09\u3001\u30a2\u30ea\u30d4\u30d7\u30e9\u30be\u30fc\u30eb\u3001\u30d6\u30ec\u30af\u30b9\u30d4\u30d7\u30e9\u30be\u30fc\u30eb\u306f1A\u30d1\u30fc\u30b7\u30e3\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u3067\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u30b7\u30ca\u30d7\u30b9\u5f8c1A\u53d7\u5bb9\u4f53\u306f\u3001\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u3092\u7e70\u308a\u8fd4\u3057\u6295\u4e0e\u3057\u3066\u3082\u8131\u611f\u4f5c\u3055\u308c\u307e\u305b\u3093[Blier]\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u7e2b\u7dda\u6838\u306b\u304a\u3051\u308b\u30b7\u30ca\u30d7\u30b9\u524d5-HT1A\u81ea\u5df1\u53d7\u5bb9\u4f53\u306e\u8131\u611f\u4f5c\u306e\u6301\u7d9a\u6642\u9593\u304c\u3001\u30bf\u30f3\u30c9\u30b9\u30d4\u30ed\u30f3\u6cbb\u7642\u306e\u4f5c\u7528\u306e\u958b\u59cb\u304c\u9045\u3044\u3053\u3068\u3092\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n<p class=\"has-background 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