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\u2460 \u30ed\u30ad\u30bd\u30d7\u30ed\u30d5\u30a7\u30f3\u306a\u3069\u3001\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6d88\u708e\u93ae\u75db\u5264<\/strong>\u3001\u2461 \u5229\u5c3f\u5264<\/strong>\u3001\u2462 \u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u5264\u3001\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u2161 \u53d7\u5bb9\u4f53\u62ee\u6297\u5264 <\/strong>\uff08\u9ad8\u8840\u5727\u6cbb\u7642\u85ac\uff09\u3001\u2463 \u30e1\u30c8\u30ed\u30cb\u30c0\u30be\u30fc\u30eb\uff08\u6297\u83cc\u85ac\uff09<\/p>\r\n\r\n\r\n\r\n

\u767a\u73fe\u983b\u5ea6\u9806\u306b\u526f\u4f5c\u7528<\/strong>\u3092\u898b\u3066\u307f\u307e\u3059\u3002
\u632f\u6226 (4.55\uff05)<\/strong>
\u53e3\u6e07 (2.40\uff05)
\u5614\u6c17\u30fb\u5614\u5410 (1.80\uff05)
\u4e0b\u75e2 (1.18\uff05)
\u8131\u529b\u30fb\u3051\u3093\u6020\u611f (1.02\uff05)
\u98df\u6b32\u4e0d\u632f 49(0.98\uff05)
\u809d\u6a5f\u80fd\u7570\u5e38 (0.90\uff05)
\u767d\u8840\u7403\u5897\u591a (0.88\uff05)
\u306d\u3080\u3051 38(0.76\uff05)
\u3081\u307e\u3044 38(0.76\uff05)<\/p>\r\n\r\n\r\n\r\n

\u9ad8\u9f62\u8005\u3078\u306e\u6295\u4e0e\u306b\u3064\u3044\u3066\u306f\u3001\u614e\u91cd\u306b\u6295\u4e0e\u3059\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b 60 \u6b73\u4ee5\u4e0a\u3067\u306f\u526f\u4f5c\u7528\u304c\u9ad8\u7387\u306b\u767a\u73fe\u3059\u308b<\/strong>\u305f\u3081\u3068\u8aac\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u814e\u6a5f\u80fd\u7b49\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u3044\u305f\u3081\u3001\u8840\u6e05\u30ea\u30c1\u30a6\u30e0\u6fc3\u5ea6\u304c\u9ad8\u304f\u306a\u308b\u304a\u305d\u308c\u304c\u3042\u308b\u3002\uff09<\/p>\r\n\r\n\r\n\r\n

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\u9577\u671f\u670d\u7528\u6642\u306e\u6ce8\u610f
\u7279\u306b\u5973\u6027\u306b\u591a\u3044\u306e\u3067\u3059\u304c\u3001\u534a\u5e74\u4ee5\u4e0a\u306e\u670d\u7528\u3067\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7<\/strong>\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u666e\u901a\u306f\u53ef\u9006\u7684\u3067\uff08\u30ea\u30c1\u30a6\u30e0\u3092\u4e2d\u6b62\u3059\u308c\u3070\u56de\u5fa9\u3059\u308b\uff09\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u6cbb\u7642\u306b\u3082\u3088\u304f\u53cd\u5fdc\u3057\u307e\u3059\u306e\u3067\u3001\u30ea\u30c1\u30a6\u30e0\u6cbb\u7642\u306e\u7d76\u5bfe\u7684\u7981\u5fcc\u306b\u306f\u3042\u305f\u308a\u307e\u305b\u3093\u3002<\/p>\r\n\r\n\r\n\r\n

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\u53cc\u6975\u6027\u969c\u5bb3\u3067\u306e\u30ea\u30c1\u30a6\u30e0\u306e\u4f7f\u7528<\/p>\r\n\r\n\r\n\r\n

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\u6025\u6027\u75c7\u72b6\u304c\u843d\u3061\u7740\u3051\u3070\u3001\u30ea\u30c1\u30a6\u30e0\u306b\u51fa\u756a\u304c\u56de\u3063\u3066\u304d\u307e\u3059\u3002\u30ea\u30c1\u30a6\u30e0\u958b\u59cb\u5f8c\u306f\u3001\u6297\u7cbe\u795e\u75c5\u85ac\u306f\u6f38\u6e1b\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/strong> \uff08\u73fe\u5728\u3067\u306f\u3001\u7b2c\u4e8c\u4e16\u4ee3\u6297\u7cbe\u795e\u75c5\u85ac\u304c\u53cc\u6975\u6027\u969c\u5bb3\u306e\u7dad\u6301\u7642\u6cd5\u306b\u3082\u7528\u3044\u3089\u308c\u307e\u3059\u3002\uff09<\/p>\r\n\r\n\r\n\r\n

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\u30ea\u30c1\u30a6\u30e0\u304c\u6709\u52b9\u306a\u60a3\u8005\u3067\u306f\u3001\u9577\u671f\u306b\u308f\u305f\u3063\u3066\u30ea\u30c1\u30a6\u30e0\u5358\u5264\u3067\u75c7\u72b6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u53ef\u80fd<\/strong>\u306a\u30b1\u30fc\u30b9\u304c\u591a\u304f\u3042\u308a\u307e\u3059\u3002<\/p>\r\n\r\n\r\n\r\n

\u5404\u6cbb\u7642\u6bb5\u968e\u3067\u306e\u30ea\u30c1\u30a6\u30e0\u6fc3\u5ea6\u306f\u3001\u6025\u6027\u671f\u3067\u3042\u308c\u30701\uff5e1.5mEq\/L\uff08\u670d\u85ac\u91cf\u306f1000\uff5e1200mg\uff09\u7a0b\u5ea6\u3001\u7dad\u6301\u7642\u6cd5\u306e\u6642\u671f\u3067\u3042\u308c\u30700.6\uff5e1mEq\/L<\/strong>\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\r\n\r\n\r\n\r\n

\u5897\u5f37\u7642\u6cd5\u3068\u3057\u3066\u306e\u30ea\u30c1\u30a6\u30e0<\/p>\r\n\r\n\r\n\r\n

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\u30ea\u30c1\u30a6\u30e0\u5897\u5f37\u7642\u6cd5<\/strong>\u304c\u6709\u52b9\u306a\u5834\u5408\u306b\u306f\u3001\u901a\u5e38\u306f2\u9031\u9593\u4ee5\u5185\u306b\u305d\u306e\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059<\/strong>\u3002<\/p>\r\n

 <\/p>\r\n

\r\n

\uff082020\/08\/15\u3000\u8ffd\u8a18\uff09<\/p>\r\n

 <\/p>\r\n

\u30ea\u30c1\u30a6\u30e0\u3068\u598a\u5a20<\/p>\r\n

\u53cc\u6975\u6027\u969c\u5bb3\u306e\u6cbb\u7642\u3067\u91cd\u8981\u306a\u4f4d\u7f6e\u3092\u5360\u3081\u308b\u30ea\u30c1\u30a6\u30e0\u3067\u3059\u304c\u3001\u598a\u5a66\u53c8\u306f\u598a\u5a20\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u5a66\u4eba\u3078\u306e\u6295\u4e0e\u306f\u7981\u5fcc\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30ea\u30c1\u30a6\u30e0\u304c\u598a\u5a20\u6642\u306b\u7981\u5fcc\u3068\u306a\u3063\u3066\u3044\u308b\u306e\u306f\u3001\u80ce\u5150\u5fc3\u5947\u5f62\u306e\u5897\u52a0\u304c\u3042\u308b\u305f\u3081\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\r\n

\u3053\u308c\u306b\u95a2\u3057\u3066\u3001\u6bd4\u8f03\u7684\u6700\u8fd1\u30012\u3064\u306e\u7814\u7a76\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306b\u3088\u308c\u3070\u3001\u4ee5\u524d\u8003\u3048\u3089\u308c\u3066\u3044\u305f\u307b\u3069\u3001\u5fc3\u5947\u5f62\u306e\u767a\u751f\u306f\u591a\u304f\u306a\u3044\u3088\u3046\u3067\u3059\u3002<\/p>\r\n

1\u3064\u3081\u306e\u7814\u7a76\u306f\u3001\u300c\u598a\u5a20\u4e2d\u306e\u30ea\u30c1\u30a6\u30e0\u4f7f\u7528\u3068\u5fc3\u5947\u5f62\u306e\u30ea\u30b9\u30af\u300d\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u3067\u3059\u3002\uff08Lithium Use in Pregnancy and the Risk of Cardiac Malformations<\/a>\uff09<\/p>\r\n

\u305d\u306e\u7d50\u679c\u3092\u898b\u308b\u3068\u3001\u5fc3\u5947\u5f62\u306e\u767a\u751f\u7387\u306f\u3001\u30ea\u30c1\u30a6\u30e0\u4f7f\u7528\u30672.41%\u3001\u975e\u4f7f\u7528\u30671.15%\u3067\u3057\u305f\u3002\uff08\u30e9\u30e2\u30c8\u30ea\u30ae\u30f3\u4f7f\u7528\u3067\u306f1.39%\uff09<\/p>\r\n

\u4f7f\u7528\u91cf\u5225\u306b\u30ea\u30b9\u30af\u6bd4\u3092\u898b\u308b\u3068\u3001
600mg\/\u65e5\u4ee5\u4e0b\u306e\u4f7f\u7528\u30671.11\u500d\u3001
601\uff5e900mg\/\u65e5\u306e\u4f7f\u7528\u30671.60\u500d\u3001
901mg\/\u65e5\u4ee5\u4e0a\u306e\u4f7f\u7528\u30673.22\u500d
\u3067\u3057\u305f<\/p>\r\n

2\u3064\u3081\u306e\u7814\u7a76\u306f\u300c\u598a\u5a20\u4e2d\u306e\u30ea\u30c1\u30a6\u30e0\u4f7f\u7528\u3068\u6bcd\u5150\u306e\u8ee2\u5e30\u300d\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u3067\u3059\u3002\uff08Maternal and infant outcomes associated with lithium use in pregnancy<\/a>\uff09<\/p>\r\n

\u598a\u5a20\u521d\u671f3\u304b\u6708\u306b\u598a\u5a66\u304c\u30ea\u30c1\u30a6\u30e0\u3092\u4f7f\u7528\u3057\u305f\u5834\u5408\u3001
\r\n\u4e3b\u8981\u306a\u5947\u5f62\u306f\u5897\u52a0\u3059\u308b\u304c\uff08\u4f7f\u75287.4%\u3001\u975e\u4f7f\u75284.3%\uff09
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\r\n\u3068\u3044\u3046\u7d50\u679c\u3067\u3057\u305f\u3002<\/p>\r\n

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