{"id":880,"date":"2020-07-09T08:41:10","date_gmt":"2020-07-08T23:41:10","guid":{"rendered":"https:\/\/kokoro-hino.tokyo\/?p=880"},"modified":"2020-08-14T10:29:19","modified_gmt":"2020-08-14T01:29:19","slug":"%e3%82%a4%e3%83%95%e3%82%a7%e3%82%af%e3%82%b5%e3%83%bcsr%ef%bc%88%e3%83%99%e3%83%b3%e3%83%a9%e3%83%95%e3%82%a1%e3%82%ad%e3%82%b7%e3%83%b3%ef%bc%89","status":"publish","type":"post","link":"https:\/\/kokoro-hino.tokyo\/?p=880","title":{"rendered":"\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\uff08\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\uff09"},"content":{"rendered":"<p>\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u304c<strong>\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u30fb\u30ed\u30b1\u30c3\u30c8\u71c3\u6599<\/strong>\uff08California rocket 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has-very-light-gray-background-color\">\u4f75\u7528\u3059\u308b\u5834\u5408\u306f\u3001<strong>\u30df\u30eb\u30bf\u30b6\u30d4\u30f3<\/strong>\uff08\u30ea\u30d5\u30ec\u30c3\u30af\u30b9\uff09\u3001\u30d6\u30d7\u30ed\u30d4\u30aa\u30f3\uff08\u672a\u767a\u58f2\uff09\u3001\u30ec\u30dc\u30ad\u30bb\u30c1\u30f3\uff08\u672a\u767a\u58f2\uff09\u3001\u30ce\u30eb\u30c8\u30ea\u30d7\u30c1\u30ea\u30f3\uff08\u30ce\u30ea\u30c8\u30ec\u30f3\uff09\u3001\u30c7\u30b7\u30d7\u30e9\u30df\u30f3\uff08\u672a\u767a\u58f2\uff09\u3001\u30de\u30d7\u30ed\u30c1\u30ea\u30f3\uff08\u30eb\u30b8\u30aa\u30df\u30fc\u30eb\uff09\u3001\u30a2\u30c8\u30e2\u30ad\u30bb\u30c1\u30f3\uff08\u30b9\u30c8\u30e9\u30c6\u30e9\uff09\u306a\u3069\u304c\u826f\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u30b9\u30bf\u30fc\u30eb\u306b\u3088\u308b\uff09\u3002<\/p>\n<p class=\"has-background 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has-very-light-gray-background-color\"><strong>\u4f4e\u7528\u91cf\u3067\u30bb\u30ed\u30c8\u30cb\u30f3\u5897\u52a0\u3001\u9ad8\u7528\u91cf\u3067\u30bb\u30ed\u30c8\u30cb\u30f3\u30fb\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u5897\u52a0\u4f5c\u7528\u3092\u793a\u3059<\/strong>\u306e\u3067\u3001\u52b9\u679c\u4e0d\u5341\u5206\u306a\u5834\u5408\u306f\u4e8c\u91cd\u52b9\u679c\u3092\u8003\u3048\u3066\u5897\u91cf\u3092\u8a66\u3059\u4fa1\u5024\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u4e2d\u6b62\u3059\u308b\u5834\u5408\u306f\u3001<strong>\u7a81\u7136\u306e\u4e2d\u65ad\u3067\u306f\u306a\u304f\u6f38\u6e1b<\/strong>\u3057\u307e\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\"><strong>\u9077\u5ef6\u6027\u3046\u3064\u75c5\u3001\u975e\u5b9a\u578b\u3046\u3064\u75c5<\/strong>\u306b\u5bfe\u3057\u3066\u512a\u4f4d\u6027\u304c\u3042\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\uff08\u30b9\u30bf\u30fc\u30eb\uff09\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u5410\u304d\u6c17\u3092\u50ac\u3057\u3084\u3059\u3044\u4eba\u3001\u9ad8\u8840\u5727\u306e\u4eba\u3001\u5fc3\u75be\u60a3\u306e\u4eba\u306b\u306f\u4f7f\u3044\u306b\u304f\u3044\u85ac\u3067\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\">\u7d50\u5408\u89aa\u548c\u6027\u3060\u3051\u3067\u306f\u8aac\u660e\u3067\u304d\u306a\u3044\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306e\u4e00\u90e8\u306f\u3001\u6d3b\u6027\u4ee3\u8b1d\u7523\u7269\u306e\u5b58\u5728\u3068\u4f4e\u3044\u86cb\u767d\u7d50\u5408\u6027\u3067\u8aac\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p class=\"has-background has-very-light-gray-background-color\"><strong>18\u624d\u672a\u6e80\u306e\u4eba\u3078\u306e\u6295\u4e0e\u306f\u63a7\u3048\u308b\u3079\u304d<\/strong>\u3067\u3059\u3002\u6709\u52b9\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u306a\u3044\u3060\u3051\u3067\u306a\u304f\u3001\u81ea\u6bba\u5ff5\u616e\u30fb\u81ea\u6bba\u884c\u52d5\u306e\u5897\u52a0\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p class=\"has-background has-pale-cyan-blue-background-color\">\u5410\u304d\u6c17\u306e\u526f\u4f5c\u7528\u304c\u5f37\u304f\u3001\u4f7f\u3044\u306b\u304f\u3044\u85ac\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001<strong>\u6cbb\u7642\u62b5\u6297\u6027\u306e\u3046\u3064\u75c5<\/strong>\u3067\u306f\u4f7f\u3063\u3066\u307f\u305f\u3044\u3001\u4f7f\u3063\u3066\u3088\u3044\u85ac\u3067\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u614e\u91cd\u306b\u526f\u4f5c\u7528\u3092\u30e2\u30cb\u30bf\u30fc\u3057\u306a\u304c\u3089\u3067\u3059\u304c\u3002<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<p>\u4ee5\u4e0b\u306f\u30a4\u30d5\u30a7\u30af\u30b5\u30fc\u306e\u6982\u7565\u3067\u3059\u3002<\/p>\n<p>\u30a4\u30d5\u30a7\u30af\u30b5\u30fc\u306f\u30011981\u5e74\u7c73\u56fd\u30ef\u30a4\u30b9\u793e\u306b\u3088\u3063\u3066\u767a\u898b\u3055\u308c\u305f\u6700\u521d\u306eSNRI\u3067\u3059\u3002\u7c73\u56fd\u3078\u306e\u5c0e\u5165\u306f1993\u5e74\u3067\u3001\u5f53\u521d\u306f\u5373\u653e\u9320\u3068\u3057\u3066FDA\u306e\u8a8d\u53ef\u3092\u5f97\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c1997\u5e74\u306b\u5f90\u653e\u30ab\u30d7\u30bb\u30eb\u5264\u306e\u30a4\u30d5\u30a7\u30af\u30b5\u30fcXR\u304cFDA\u306e\u8a8d\u53ef\u3092\u5f97\u3066\u30012009\u5e74\u306b\u30ef\u30a4\u30b9\u793e\u304c\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u306b\u53d6\u308a\u8fbc\u307e\u308c\u308b\u307e\u3067\u3001\u5373\u653e\u9320\u3068\u5f90\u653e\u30ab\u30d7\u30bb\u30eb\u306e\u4e21\u8005\u304c\u4f75\u58f2\u3055\u308c\u307e\u3057\u305f\u3002\u73fe\u5728\u30d5\u30a1\u30a4\u30b6\u30fc\u793e\u306f\u5f90\u653e\u30ab\u30d7\u30bb\u30eb\u306e\u307f\u88fd\u9020\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306f\u3001\u5f90\u653e\u30ab\u30d7\u30bb\u30eb\u304c1\u65e51\u56de\u306e\u670d\u7528\u3067\u6e08\u3080\u3053\u3068\u3001\u5373\u653e\u9320\u3068\u6bd4\u3079\u3066\u5614\u6c17\u306e\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u3053\u3068\u306e\u3088\u3046\u3067\u3059\u3002<\/p>\n<p>\u6211\u304c\u56fd\u3067\u306f\u3001\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u306e\u540d\u79f0\u3067\u5f90\u653e\u6027\u30ab\u30d7\u30bb\u30eb\u304c2015\u5e7412\u6708\u3088\u308a\u8ca9\u58f2\u958b\u59cb\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u69cb\u9020\u5f0f<\/span><\/strong><\/span><br \/>\n<img loading=\"lazy\" class=\"alignnone wp-image-881\" src=\"http:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-14_53_17-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF.jpg\" alt=\"\" width=\"297\" height=\"122\" srcset=\"https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-14_53_17-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF.jpg 679w, https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-14_53_17-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF-300x123.jpg 300w\" sizes=\"(max-width: 297px) 100vw, 297px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" class=\"alignnone wp-image-911\" src=\"http:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/effexor.jpg\" alt=\"\" width=\"335\" height=\"268\" srcset=\"https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/effexor.jpg 430w, https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/effexor-300x240.jpg 300w\" sizes=\"(max-width: 335px) 100vw, 335px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u9069\u5fdc\uff08\u52b9\u80fd\u53c8\u306f\u52b9\u679c\uff09<\/span><\/strong><\/span><br \/>\n\u3046\u3064\u75c5\u30fb\u3046\u3064\u72b6\u614b<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u7528\u6cd5\u53ca\u3073\u7528\u91cf<\/span><\/strong><\/span><br \/>\n1 \u65e5 1 \u56de\u98df\u5f8c\u306b\u7d4c\u53e3\u6295\u4e0e<br \/>\n\u521d\u671f\u7528\u91cf 37.5 mg\u30011 \u9031\u5f8c\u3088\u308a 75 mg\uff08225 mg \u3092\u8d85\u3048\u306a\u3044\u7bc4\u56f2\u3067\u9069\u5b9c\u5897\u6e1b\uff09<\/p>\n<p>\u7528\u6cd5\u53ca\u3073\u7528\u91cf\u306b\u95a2\u9023\u3059\u308b\u6ce8\u610f<br \/>\n\u5897\u91cf\u306b\u3088\u308a\u4e0d\u7720\u75c7\u72b6\u3001\u8840\u5727\u4e0a\u6607\u7b49\u306e\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u7528\u304c\u3042\u3089\u308f\u308c\u308b\u304a\u305d\u308c\u304c\u3042\u308b\u3002<br \/>\n\u809d\u6a5f\u80fd\u969c\u5bb3\u306e\u3042\u308b\u60a3\u8005\u3067\u306f\u3001\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u526f\u4f5c\u7528\u304c\u767a\u73fe\u3057\u3084\u3059\u304f\u306a\u308b\u304a\u305d\u308c\u304c\u3042\u308b\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u4f5c\u7528\u6a5f\u5e8f\u30a4\u30e1\u30fc\u30b8<\/span><\/strong><\/span>\uff08 in vitro \uff09\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0\u3088\u308a<br \/>\n<img loading=\"lazy\" class=\"alignnone wp-image-882\" src=\"http:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-15_10_14-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF.jpg\" alt=\"\" width=\"\" height=\"\" srcset=\"https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-15_10_14-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF.jpg 918w, https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-15_10_14-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF-300x114.jpg 300w, https:\/\/kokoro-hino.tokyo\/wp-content\/uploads\/2020\/07\/2020-07-08-15_10_14-efx01if.pdf-\u30a4\u30d5\u30a7\u30af\u30b5\u30fcSR\u30ab\u30d7\u30bb\u30eb37.5mg75mg_\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0-SumatraPDF-768x292.jpg 768w\" sizes=\"(max-width: 918px) 100vw, 918px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u85ac\u7406\u52b9\u679c<\/span><\/strong><\/span><br \/>\n\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\u3068\u305d\u306e\u6d3b\u6027\u4ee3\u8b1d\u7523\u7269\u3067\u3042\u308bO -\u8131\u30e1\u30c1\u30eb\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\uff08ODV\uff09\u304c\u85ac\u7406\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u3002<br \/>\n\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u3068\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u4f5c\u7528\u3068\u5f31\u3044\u30c9\u30d1\u30df\u30f3\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u4f5c\u7528\u3092\u6709\u3059\u3002<br \/>\n\u6d3b\u6027\u4ee3\u8b1d\u7523\u7269ODV\u306f\u3001\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\u3068\u540c\u7b49\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u30fb\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u4f5c\u7528\u3068\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\u3088\u308a\u3055\u3089\u306b\u5f31\u3044\u30c9\u30d1\u30df\u30f3\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u4f5c\u7528\u3092\u6709\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u8840\u4e2d\u6fc3\u5ea6\u306e\u63a8\u79fb<\/span><\/strong><\/span><\/p>\n<p>\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3:<br \/>\n\u6700\u9ad8\u8840\u4e2d\u6fc3\u5ea6\u5230\u9054\u00a06 \u6642\u9593<br \/>\n\u534a\u6e1b\u671f\u7d049\u6642\u9593<\/p>\n<p>ODV:<br \/>\n\u6700\u9ad8\u8840\u4e2d\u6fc3\u5ea6\u5230\u9054\u00a0 8\uff5e10 \u6642\u9593<br \/>\n\u534a\u6e1b\u671f\u7d0412\u6642\u9593<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u98df\u4e8b\u306e\u5f71\u97ff<\/span><\/strong><\/span><br \/>\n\u98df\u4e8b\u306b\u3088\u308b\u85ac\u7269\u52d5\u614b\u3078\u306e\u5f71\u97ff\u306f\u307f\u3089\u308c\u306a\u3044\u304c\u3001\u7a7a\u8179\u6642\u3088\u308a\u98df\u5f8c\u306e\u65b9\u304c\u3088\u308a\u9ad8\u3044\u5b89\u5168\u6027\u304c\u671f\u5f85\u3055\u308c\u308b\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u4ee3\u8b1d<\/span><\/strong><\/span><br \/>\n\u4e3b\u3068\u3057\u3066 <strong>CYP2D6<\/strong>\u3001\u4e00\u90e8 <strong>CYP3A4<\/strong> \u3067\u4ee3\u8b1d\u3055\u308c\u308b\u3002<\/p>\n<p>\uff08CYP \u963b\u5bb3\uff1aCYP2D6\u306b\u5bfe\u3057\u3066\u5f31\u3044\u963b\u5bb3\u4f5c\u7528\u3092\u793a\u3059\uff09<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u7981\u5fcc\uff08\u6b21\u306e\u60a3\u8005\u306b\u306f\u6295\u4e0e\u3057\u306a\u3044\u3053\u3068\uff09<\/span><\/strong><\/span><br \/>\n1 \u672c\u5264\u306e\u6210\u5206\u306b\u5bfe\u3057\u904e\u654f\u75c7\u306e\u65e2\u5f80\u6b74\u306e\u3042\u308b\u60a3\u8005<br \/>\n2 \u30e2\u30ce\u30a2\u30df\u30f3\u9178\u5316\u9175\u7d20\uff08MAO\uff09\u963b\u5bb3\u5264\u3092\u6295\u4e0e\u4e2d\u3042\u308b\u3044\u306f\u6295\u4e0e\u4e2d\u6b62\u5f8c2\u9031\u9593\u4ee5\u5185\u306e\u60a3\u8005<br \/>\n3 \u91cd\u5ea6\u306e\u809d\u6a5f\u80fd\u969c\u5bb3\uff08Child-Pugh\u5206\u985eC\uff09\u306e\u3042\u308b\u60a3\u8005<br \/>\n4 \u91cd\u5ea6\u306e\u814e\u6a5f\u80fd\u969c\u5bb3\uff08\u7cf8\u7403\u4f53\u308d\u904e\u91cf15 mL\/min\u672a\u6e80\uff09\u306e\u3042\u308b\u60a3\u8005\u53c8\u306f\u900f\u6790\u4e2d\u306e\u60a3\u8005<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-family: 'arial black', sans-serif; color: #0000ff;\"><strong>\u526f\u4f5c\u7528\u3000<\/strong><\/span>3\uff05\u4ee5\u4e0a\u306e\u3082\u306e\uff08\u56fd\u5185\u81e8\u5e8a\u8a66\u9a13 1255 \u4f8b\uff09<\/p>\n<table style=\"border-color: #000000; width: 343px; background-color: #ecdfed;\" width=\"343\">\n<tbody>\n<tr>\n<td style=\"width: 257px;\">\u60aa\u5fc3<\/td>\n<td style=\"width: 70px;\">33.5\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u8179\u90e8\u4e0d\u5feb\u611f\uff08\u8179\u75db\u3001\u81a8\u6e80\u3001\u4fbf\u79d8\u7b49\u3092\u542b\u3080\uff09<\/td>\n<td style=\"width: 70px;\">27.2\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u50be\u7720<\/td>\n<td style=\"width: 70px;\">26.9\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u6d6e\u52d5\u6027\u3081\u307e\u3044<\/td>\n<td style=\"width: 70px;\">24.4\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u53e3\u5185\u4e7e\u71e5<\/td>\n<td style=\"width: 70px;\">24.3\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u982d\u75db<\/td>\n<td style=\"width: 70px;\">19.3\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u4e0d\u7720\u75c7<\/td>\n<td style=\"width: 70px;\">16\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u52d5\u60b8<\/td>\n<td style=\"width: 70px;\">13.2\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u809d\u6a5f\u80fd\u691c\u67fb\u5024\u7570\u5e38\uff08ALT\uff08GPT\uff09\u30fbAST\uff08GOT\uff09\u30fb\u03b3-GTP\u30fbLDH\u30fbAl-P\u30fb\u8840\u4e2d\u30d3\u30ea\u30eb\u30d3\u30f3\u306e\u4e0a\u6607\u7b49\uff09<\/td>\n<td style=\"width: 70px;\">10\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u5614\u5410<\/td>\n<td style=\"width: 70px;\">8.7\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u611f\u899a\u5668\u8abf\u7bc0\u969c\u5bb3<\/td>\n<td style=\"width: 70px;\">8.5\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u6392\u5c3f\u56f0\u96e3<\/td>\n<td style=\"width: 70px;\">6.6\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u9f3b\u54bd\u982d\u708e<\/td>\n<td style=\"width: 70px;\">6.3\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u767a\u6c57\uff08\u5bdd\u6c57\u3092\u542b\u3080\uff09<\/td>\n<td style=\"width: 70px;\">6.2\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u7121\u529b\u75c7\uff08\u75b2\u52b4\u3001\u5026\u6020\u611f\u3092\u542b\u3080\uff09<\/td>\n<td style=\"width: 70px;\">5.7\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u4e0b\u75e2<\/td>\n<td style=\"width: 70px;\">5.3\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u4f53\u91cd\u6e1b\u5c11<\/td>\n<td style=\"width: 70px;\">5.3\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u8840\u6db2<\/td>\n<td style=\"width: 70px;\">4.5\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u98df\u6b32\u6e1b\u9000<\/td>\n<td style=\"width: 70px;\">4.3\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u8840\u5727\u4e0a\u6607<\/td>\n<td style=\"width: 70px;\">3.9\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u904e\u654f\u75c7<\/td>\n<td style=\"width: 70px;\">3.7\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u983b\u8108<\/td>\n<td style=\"width: 70px;\">3.7\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u7570\u5e38\u611f\u899a\uff08\u932f\u611f\u899a\u3001\u611f\u899a\u920d\u9ebb\u7b49\uff09<\/td>\n<td style=\"width: 70px;\">3.6\uff05<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 257px;\">\u8840\u4e2d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5897\u52a0<\/td>\n<td style=\"width: 70px;\">3.1\uff05<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">IC50\uff0850%\u963b\u5bb3\u6fc3\u5ea6\uff09<\/span><\/strong><\/span><\/p>\n<p>\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3<br \/>\n5-HT\uff1a0.19\uff5e0.21 \u03bcmol\/L<br \/>\nNA\uff1a0.64\uff5e0.72 \u03bcmol\/L<br \/>\nDA\uff1a2.8 \u03bcmol\/L<\/p>\n<p>ODV<br \/>\n5-HT\uff1a0.18\uff5e0.20 \u03bcmol\/L<br \/>\nNA\uff1a1.16 \u03bcmol\/L<br \/>\nDA\uff1a13.4 \u03bcmol\/L<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/en.wikipedia.org\/wiki\/Venlafaxine#cite_note-58\"><span style=\"color: #0000ff;\"><strong><span style=\"font-family: 'arial black', sans-serif;\">\u7d50\u5408\u89aa\u548c\u6027<\/span><\/strong><\/span><\/a><\/p>\n<p>\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3<br \/>\n\uff08\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u3001Ki\u00a0[nM]\uff09<br \/>\nSERT 82<br \/>\nNET 2480<br \/>\nDAT 7647<br \/>\n\uff08\u53d7\u5bb9\u4f53\u3001Ki\u00a0[nM]\uff09<br \/>\n5-HT2A 2230<br \/>\n5-HT2C 2004<br \/>\n5-HT6 2792<br \/>\n\u03b11A &gt;1000<\/p>\n<p>\u30bb\u30ed\u30c8\u30cb\u30f3 5-HT 1 \u30015-HT 1A \u53ca\u3073 5-HT 2 \u53d7\u5bb9\u4f53\u3001\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u03b1 1 \u3001\u03b1 2 \u53ca\u3073\u03b2\u53d7\u5bb9\u4f53\u3001\u30d2\u30b9\u30bf\u30df\u30f3 H 1 \u53d7\u5bb9\u4f53\u3001\u975e\u9078\u629e\u7684\u30c9\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\u3001\u30c9\u30d1\u30df\u30f3 D 1 \u53ca\u3073 D 2 \u53d7\u5bb9\u4f53\u3001\u30e0\u30b9\u30ab\u30ea\u30f3\u53d7\u5bb9\u4f53\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u53d7\u5bb9\u4f53\u3001 N -\u30e1\u30c1\u30eb-D-\u30a2\u30b9\u30d1\u30e9\u30ae\u30f3\u9178\uff08NMDA\uff09\u53d7\u5bb9\u4f53\u3001NMDA \u53d7\u5bb9\u4f53\u30d5\u30a7\u30f3\u30b5\u30a4\u30af\u30ea\u30b8\u30f3\uff08PCP\uff09\u7d50\u5408\u90e8\u4f4d\u53ca\u3073 GABA A \u53d7\u5bb9\u4f53\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u7d50\u5408\u90e8\u4f4d\u306b\u5bfe\u3057\u3066\u7d50\u5408\u89aa\u548c\u6027\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u3002\uff08IF\u3088\u308a\uff09<\/p>\n<p>ODV<br \/>\n\u30bb\u30ed\u30c8\u30cb\u30f3 5-HT 2 \u3001\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u03b1 1 \u3001\u30d2\u30b9\u30bf\u30df\u30f3 H 1 \u3001\u30c9\u30d1\u30df\u30f3 D 2 \u3001\u30e0\u30b9\u30ab\u30ea\u30f3\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u3001NMDA \u53ca\u3073 NMDA \u53d7\u5bb9\u4f53 PCP\u7d50\u5408\u90e8\u4f4d\u306b\u5bfe\u3057\u3066\u7d50\u5408\u89aa\u548c\u6027\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u3002\uff08IF\u3088\u308a\uff09<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u30fb\u30ed\u30b1\u30c3\u30c8\u71c3\u6599\uff08California rocket 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